Volume 13, Issue 1
Original Article / Published: September 2025
DOI: https://www.doi.org/10.57045/jemis/1310925.pp44-51
El-Tal L.
Acibadem City Clinic Tokuda Hospital, Sofia, Department of liver, biliary, pancreatic and general surgery
Abstract
Introduction: Today, chronic pancreatitis is a well-studied disease. Geographical distribution depends on social and geographical factors. The most common etiological factors are alcohol consumption and smoking. Genetic predisposition in familial cases is linked to gene mutations. As the disease progresses, exocrine dysfunction and insulin-dependent diabetes mellitus may occur. Chronic inflammation of the pancreatic parenchyma is associated with a higher incidence of pancreatic cancer. Surgical treatment is indicated in cases of associated chronic pain syndrome, complications, pancreatic tumors. In practice, two main surgical approaches have been introduced to improve the patienta’s condition – internal ductal drainage, resection and combinations between them.
The aim of the study: Evaluation of the different pathomorphological changes in chronic pancreatitis, its complications and different surgical approaches.
Material and method: A literature review of the various changes in the pancreas, complications associated with chronic pancreatitis, difficulties in diagnosis and surgical approaches. Discussion: In its progression, chronic pancreatitis leads to the appearance of various changes in the pancreatic gland, surrounding tissues and organs. It may be associated with a difficult differential diagnosis with pancreatic tumors, complicated peptic ulcer disease, vascular anomalies. Changes in the pancreatic duct associated with chronic pancreatitis are common. Dilatation of the main pancreatic duct associated with chronic pain syndrome is indicated for surgical decompression with very good results in pain resolution in association with preservation of pancreatic function. Pseudotumor changes in the gland are often difficult to distinguish from pancreatic tumors and complicated duodenal ulcer with penetration of the pancreatic head. The best way of treatment in these cases is resection surgery
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Keywords:
chronic pancreatitis, surgical approaches, complications
How to cite this article:
El-Tal L. Surgical therapy of chronic pancreatitis: Indications, techniques and results. Journal of Endourology and Minimally Invasive Surgery (Bulgaria), 2025; 13(1): 44-51
Corresponding author:
Dr. L. El-Tal
Clinic of Hepatobiliary, Pancreatic and General Surgery
Acibadem City Clinic Tokuda Hospital
51B Nikola Vaptsarov Blvd
e-mail: luben.eltal@gmail.com