Volume 13, Issue 1
Original Article / Published: September 2025
DOI: https://www.doi.org/10.57045/jemis/1310925.pp34-43
I.Gergova1, T. Badarov2
1Microbiology Laboratory, Department of Microbiоlogy, Virology, Clinical laboratory and Immunology, Military Medical Academy of Sofia, 2Clinic of Urology, Department of Urology and Nephrology, Military Medical Academy, Sofia, Bulgarian Clinic of Thoracic surgery, Department of Thoracic Surgery, Pneumology, Phthisiology and Endocrinology, and Metabolic Diseases, Military Medical Academy of Sofia
Abstract
The skin microbiome is characterized by a significant species diversity and specificity in different topographical zones. Initial studies on the composition and functions of the microbiome have focused on classifying microorganisms as pathogens or opportunistic pathogens. It is generally accepted that pathogens play a key role in the onset and progression of infections, but the functional importance of commensal skin microbiota in these processes is still under investigation. Currently, the microbiome is considered a complcated and dynamic complex, functioning on the basis of established interactions among microorganisms themselves, on one hand, and between the microbiota as a whole and the host, on the other. Identifying the composition of the microbiota of healthy skin and establishing the mechanisms of microbial interactions continue to be the subject of extensive research aimed at better understanding the pathogenesis of skin diseases and infections, with a view to improving therapy.
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Keywords:
Microbiota, Microbial interactions, Skin microbiome
How to cite this article:
I. Gergova, T. Badarov. Human skin microbiome: structure, functions, perspectives. Journal of Endourology and Minimally Invasive Surgery (Bulgaria), 2025; 13(1): 34-43
Corresponding author:
Assoc. Prof. Ivanka Gergova, MD, PhD
Military Medical Academy -Sofia, Department of Microbiology, Virology, Clinical laboratory and
Immunology,
3 Georgi Sofijsky Str., Sofia 1606
e-mail: gergova.ivana7@gmail.com